Table 2 Univariate Cox regression analysis

From: Systemic inflammatory markers have independent prognostic value in patients with metastatic testicular germ cell tumours undergoing first-line chemotherapy

 

Overall survival

 

HR (95% CI)

P -value

IGCCCG risk groups Good risk

Intermediate risk

Poor risk

Reference

0.509 (0.061–4.24)

7.44 (2.73–20.3)

<0.001

0.53

0.001

Haemoglobin (g l−1)

0.962 (0.942–0.982)

<0.001

Platelets (103 per μl)

1.004 (1.000–1.009)

0.069

Leukocytes (103 per μl)

1.136 (1.14–1.565)

<0.001

Neutrophils (103 per μl)

1.611 (1.23–2.105)

<0.001

Lymphocytes (103 per μl)

0.497 (0.127–1.940)

0.31

CRP (mg l−1)

6.44 (2.04–20.29)

0.001

Albumin (g l−1)

0.844 (0.742–0.961)

0.010

NLRa

73.1 (3.70–1442)

0.005

PLRa

8.42 (0.72–98.7)

0.090

SIIa

30.2 (3.00–304)

0.004

  1. Abbreviations: CI=confidence interval; CRP=C-reactive protein; HR=hazard ratio; IGCCCG=International Germ Cell Cancer Collaborative Group; IQR=interquartile range; NLR=neutrophils-to-lymphocytes ratio; PLR=platelets-to-lymphocytes ratio; SII=systemic immune-inflammation index.
  2. aAfter log10 transformation: the HR thus corresponds to a 10-fold increase of the variable, bold P-values indicate statistical significance.