Figure 5 | British Journal of Cancer

Figure 5

From: Health-related quality of life impact of cobimetinib in combination with vemurafenib in patients with advanced or metastatic BRAFV600 mutation–positive melanoma

Figure 5

Impact of select AEs on global health status. Clinically meaningful change is defined as a ⩾10-point change from baseline. Error bars are standard error of mean (SEM). Each treatment cycle was 28 days, with vemurafenib administered on days 1–28 and cobimetinib administered on days 1–21, followed by a 7-day rest period. AE=adverse event.

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