Table 5 Prognostic indicators for breast cancers diagnosed in regular vs irregularly screeneda women, New Zealand women aged 45–69 years at year of diagnosis, 2003–2011b
Regularly screened | Irregularly screened | ||||
---|---|---|---|---|---|
Prognostic indicator | n | % | n | % | Significance of difference |
Grade of tumour | |||||
Well differentiated | 1697 | 30.6 | 2160 | 29.7 | χ2(1)=1.38, P=0.2403 |
Excluding not recorded or NA (n=696) | 32.1 | 31.6 | χ2(1)=0.38, P=0.5381 | ||
Moderately differentiated | 2315 | 41.8 | 2960 | 40.6 | |
Poorly or undifferentiatedor anaplastic | 1277 | 23 | 1724 | 23.7 | |
Not recorded/NA | 255 | 4.6 | 441 | 6.1 | |
Overall heterogeneity: χ2(3)=14.7, P=0.0021 | |||||
Extent of disease | |||||
Localised | 3738 | 67.4 | 4333 | 59.5 | χ2(1)=85.2, P<0.0001 |
Excluding unknown (n=847) | 71.6 | 64.1 | χ2(1)=74.1, P<0.0001 | ||
Adjacent organ or | |||||
regional lymph node | 1433 | 25.9 | 2310 | 31.7 | |
Distant | 53 | 1 | 115 | 1.6 | |
Distant÷(distant+regional) | 3.6 | 4.7 | RR=0.75 (0.55–1.03) | ||
Unknown | 320 | 5.8 | 527 | 7.2 | χ2(1)=3.10, P=0.0784 |
Overall heterogeneity: χ2(3)=93, P<0.0001 | |||||
Multiple tumours | |||||
No | 5475 | 98.8 | 7127 | 97.8 | RR=0.57 (0.43–0.76) |
Yes | 69 | 1.2 | 158 | 2.2 | χ2(1)=15.5, P<0.0001 |
Maximum tumour size | (mm) | (mm) | |||
Mean | 16.3 | 19.3 | t=−12.0, P<0.0001 | ||
Median | 14 | 15 | z=−10.5, P<0.0001c |