Table 1 Pre-transplant characteristics, engraftment, toxicity and outcome in patients undergoing RIC HSCT for myelofibrosis

From: A reduced intensity conditioning protocol associated with excellent survival in patients with myelofibrosis

Age/sex

Time from diagnosis to transplant (months)

Risk factors/Lillee score

Donor

CD ( × 10 6 CD34/kg)

ANC>0.5/Plt >20

Infections

Toxicity & GVHD

Outcome (months)

56/F

14

Nil/2

HSD

8.4

24/28

Nil

Nil

Alive (24)

40/M

243

t(4;13)/1

HSD

10.0

18/26

Pseudo

Nil

Alive (20)

51/M

41

CK/1

MUD

10.0

17/29

S. Epi

Nil

Alive (19)

54/M

10

Splenectomy/2

HSD

2.4

18/28

CMV

Nil

Alive (14)

55/F

11

CK/2

MUD

10.5

20/19

Nil

Nil

Alive (12)

52/F

50

Nil/1

HSD

7.3

17/157

CMV

Grade II GVHD

Alive (10)

  1. Abbreviations: CD=cell dose; CK=complex karyotype; HSD=HLA identical sibling donor; MUD=Matched unrelated donor; Plt=Platelet count; Pseudo=Pseudomonas aeruginosa; S. Epi=Staphylococcus epidermidis.
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