Table 1 Demographic and clinical data of the patients

From: Surveillance for adenovirus DNAemia early after transplantation in adult recipients of unrelated-donor allogeneic stem cell transplants in the absence of clinically suspected infection

Parameter

No. of patients (%)

Age, median (range)

44 (18–64)

Sex, male patients/female patients

25 (56.8)/19 (43.2)

Underlying disease

 AML

16 (36.3)

 Non-Hodgkin's lymphoma

8 (18.1)

 Myelodysplastic syndrome

7 (15.9)

 ALL

3 (6.8)

 Plasma cell disorders

3 (6.8)

 CLL

2 (4.5)

 CML

2 (4.5)

 Hodgkin's lymphoma

2 (4.5)

 Aplastic anemia

1 (2.3)

Donor type

 Matched unrelated

22 (50.0)

 Mismatched unrelated

22 (50.0)

Conditioning regimen

 Myeloablative

29 (65.9)

 Myeloablative

15 (34.1)

Stem cell source

 Peripheral blood

29 (69.5)

 Umbilical cord blood

14 (31.8)

 Bone marrow

1 (2.3)

ATG treatment

 Yes

28 (63.6)

 No

16 (36.4)

Acute GVHD

 Grades 0 and I

31 (70.4)

 Grades II–IV

13 (29.6)

Active CMV infection pre-emptively treated a

 Yes

35 (79.5)

 No

9 (20.5)

CMV end-organ disease b

 Yes

3 (6.8)

 No

41 (93.2)

  1. Abbreviation: ATG=antithymocyte globulin.
  2. aActive CMV infection was diagnosed by a plasma real-time PCR assay (CMV real-time PCR; Abbott Molecular, Des Plaines, IL, USA, or LightCycler CMV Quant Kit, Roche, Branchburg, NJ, USA), or by the pp65 antigenemia assay (Diagnostics CMV pp65 Antigenemia Immunofluorescence assay; Chemicon International, Temecula, CA, USA).
  3. bEnteritis.