Table 1 Characteristics, treatment and outcome of the five transplanted patients with H1N1 infection in the study

From: The impact of novel influenza A (H1N1) after hematopoietic SCT

Case

Age/ gender

Diagnosis

Type of matched donor

Time from transplant (months)

Conditioning regimens a

Previous GVHD

Immuno- suppression at the time of H1N1

Duration of immuno- suppression

Lower respiratory tract infection

Co-infection with other pathogen

Treatment (days)

Outcome

1

51/M

ALL

Related

19

Flu/Bu

Yes

None

NA

Yes

No

Oseltamivir 5 days

Complete resolution

2

46/F

Myelofibrosis

Unrelated

7

Flu/Mel/ATG

Yes

Prednisone

Tacrolimus

5 months

7 months

No

No

Oseltamivir 5 days

Complete resolution

3

23/M

Lymphoblastic lymphoma

Related

12

TBI/Cy/ VP-16

Yes

Tacrolimus

2 months

No

No

Oseltamivir 5 days

Complete resolution

4

56/F

MDS

Related

18

Flu/Bu

Yes

Prednisone

MMF

Tacrolimus

2 months

13 months

1 month

Yes

Yes

Oseltamivir 14 days

Peramivir

10 days

Death

5

53/F

AML

Autologous

3

Flu/Bu

NA

NA

NA

Yes

No

Oseltamivir 5 days

Complete resolution

  1. Abbreviations: MDS=myelodysplastic syndrome; MMF=mycophenolate mofetil; NA=not applicable.
  2. aConditioning regimens: fludarabine 160 mg/m2–i.v. BU 12.8 mg/kg (Flu/Bu); fludarabine 150 mg/m2–melphalan 140 mg/m2–thymoglobulin 4.5 mg/kg (Flu/Mel/ATG); TBI 12 Gy (fractionated)–CY 120 mg/kg–etoposide 45 mg/kg (TBI/Cy/VP-16).