Table 1 Patient characteristics

From: Risk factors for hypogammaglobulinemia after allo-SCT

 

Variable

All SCT patients (n=278),

total 299 SCT

Sex

Male/female

147/131

Age (years)

Median (range)

46 (17–69)

 

Over/under 55

91/187

Disease

AML/MDS/ALL/ML/ATL/CML/AA

102/30/39/62/22/12/8

 

Lymphoid malignancy Y (with RTX)/N

123 (31)/155

SCT risk

High/standard

158/141

Disease status

Progressive/controlled

95/204

Previous allo-SCT

Y/N

34/265

Donor source

Related/unrelated-BM/CB

118/130/51

 

HLA allele mismatch (excluding CB) Y/N

52/197

Conditioning

MAC (TBI Y/N)

164 (136/28)

 

RIST (TBI Y/N)

135 (92/43)

aGVHD prophylaxis

CsA/FK506 based

60/239

 

+MTX/+MMF/Both

190/16/46

Pre-SCT IgG (mg/dL)

Median (range)

973 (140–2271)

 

Under/over 800

101/198

Follow-up (day)

Median (range)

1968 (98–4724)

  1. Abbreviations: AA=aplastic anemia; aGVHD=acute GVHD; ATL=adult T-cell leukemia; CB=cord blood; MAC=myeloablative conditioning; MDS=myelodysplastic syndrome; ML=malignant lymphoma; MMF=mycophenolate mofetil; RIST=reduced-intensity SCT; RTX=rituximab therapy.