Figure 1 | Bone Marrow Transplantation

Figure 1

From: Influence of glutathione S-transferase gene polymorphisms on busulfan pharmacokinetics and outcome of hematopoietic stem-cell transplantation in thalassemia pediatric patients

Figure 1

Influence of GSTA1 C-69 T on the first dose of Bu pharmacokinetics. The pharmacokinetic parameters of Bu in relation to CC, CT and TT genotypes in all studied patients. Respective mean±SD values adjusted for Bu dose (mg/kg) are for logCss (steady state concentration): 2.9±0.08, 2.9±0.1 and 3.0±0.3, and for logAUC (area under the curve): 5.4±0.09, 5.4±0.1 and 5.5±0.3. The number of individuals represented for each genotype group as well as P-values for the difference across groups is given on each plot.

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