Table 1 Titers of antinuclear antibody and auto-Abs before and after allogeneic-hematopoietic stem cell transplantation
Normal range | Before AML | Onset of AML | Recurrence of AML | Post allo-HSCT | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
50 D | 6 M | 12 M | 18 M | 24 M | 42 M | Last follow-up | |||||
ANA | ~640 | 40 | 40 | 40 | 40 | 40 | 80 | NA | 640 | 320 | |
Staining pattern of ANA | Homo, Spec | Spec | Homo | Homo | Nucleolar | Nucleolar | Nucleolar | NA | Nucleolar | Nucleolar | |
Anti-ssDNA Ab | <40 AU/mL | ~100 | NA | NA | 24.4 | NA | NA | NA | NA | NA | — |
Anti-ssDNA IgG-Ab | <7 U/mL | — | — | — | — | — | — | — | — | — | 5.3 |
Anti-dsDNA Ab | <20 IU/mL | ~40.2 | 12.4 | 8 | 2.8 | 2.4 | 2.5 | 4.5 | NA | NA | — |
Anti-dsDNA IgG-Ab | <10 IU/mL | — | — | — | — | — | — | — | — | — | 1.3 |
Anti-Ro/SS-A Ab | <10 U/mL | ~32.5 | 11.9 | 9.9 | <7.0 | <7.0 | <7.0 | <5.0 | NA | NA | 0.8 |
Anti-TPO Ab | <0.1 U/mL | positive | 91.7 | 53.4 | 23.4 | 0.5 | <0.3 | <0.3 | — | — | — |
<15 IU/mL | — | — | — | — | — | — | 8 | 29 | 103 | 149 | |
Chimerism (% donor) | — | — | — | 100 | 100 | 100 | 100 | 100 | 100 | 100 | |
