Table 1 Patients characteristics
Features | H-ASCT (N=22) | NH-ASCT (N=22) | P-value |
|---|---|---|---|
Age (years; mean±s.e.m.) | 51.2±3.2 | 50.9±3.1 | NS |
Sex M/F (ratio) | 11/11 (0.5) | 16/6 (0.73) | NS |
Previous transplantation | 8 | 2 | NS |
Disease status (CR/non-CR) | 16/6 | 15/7 | NS |
Graft source | |||
Genoidentical/phenoidentical | − | 14/7/1 | |
10/10/phenoidentical 9/10 | |||
No. of CD34+ cells infused (106/kg) | 7.7±0.7 | 6.3±0.6 | NS |
Conditioning (RIC, MAC, Sequential) | 19/0/3 | 14/6/2 | |
Fludarabine/Clofarabine based | 12/7 | 18/4 | NS |
Donor/recipient sex match (M/M, F/M, M/F, F/F) | 8/8/3/3 | 13/1/3/5 | NS |
PMN recovery (median, 95% CI, days) | 18 (17–22) | 18.5 (17–20) | NS |
RBC recovery (median, 95% CI, days) | 22 (15–32) | 10 (4–18) | 0.0018 |
Plt recovery (median, 95% CI, days) | 26.5 (18–51.5) | 10.5 (9–13) | 0.004 |
RBC transfusions (median, 95% CI) | 7 (4–8) | 2 (2–4) | 0.0014 |
Plt transfusions (median, 95% CI) | 11 (7–21) | 3 (2–10) | 0.005 |
