Table 2 Cox model for OS

From: Validation of the revised IPSS at transplant in patients with myelodysplastic syndrome/transformed acute myelogenous leukemia receiving allogeneic stem cell transplantation: a retrospective analysis of the EBMT chronic malignancies working party

 

Hazard ratio

Lower limit 95%CI

Upper limit 95% CI

P-value

a. Univariate Cox model for IPSS-R

IPSS-R

   

<0.001

 Very low

0.518

0.251

1.068

0.075

 Low

0.444

0.322

0.612

<0.001

 Intermediate

0.607

0.448

0.822

0.001

 High

0.711

0.529

0.956

0.024

 Very high

1

   

b. Multivariate Cox model for the components of IPSS-R

Genetic risk group a

   

<0.001

 0

1

   

 1

3.933

0.958

16.148

0.057

 2

4.013

0.986

16.339

0.052

 3

4.607

1.118

18.980

0.034

 4

9.614

2.292

40.332

0.002

Blasts

   

0.004

 <2%

1

   

 2–5%

1.025

0.744

1.412

0.881

 5–10%

1.311

0.968

1.775

0.080

 >10%

1.697

1.250

2.302

0.001

Hemoglobin x109/l

   

0.912

 >10 g/dL

1

   

 8–10 g/dL

1.045

0.806

1.356

0.738

 <8 g/dL

0.986

0.701

1.386

0.934

Platelets x109/l

   

0.721

 >100

1

   

 50–100

1.069

0.792

1.444

0.663

 <50

1.120

0.850

1.476

0.420

ANC x109/l

 >0.8

1

   

 <0.8

1.298

0.996

1.690

0.053

  1. Abbreviations: IPSS-R=revised International Prognostic Scoring System; OS=overall survival.
  2. aAccording to Schanz et al.5
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