Figure 4
From: Contaminated open fracture and crush injury: a murine model
Bones from injured limbs were studied via Microfil perfusion followed by decalcification and microCT scanning. Reconstructed images of vascular casts within the blue shadow of bone from limbs with bacteria at 1-week (a), 2-week (b) and 4-week (c) time points are shown in the top row. The proximal femur segment is toward the bottom of each image. The gap between the femur segments has been allowed to compress for imaging purposes. Representative reconstructive images from injured legs without bacteria are shown in the bottom row at the same time points (d–f). Total vessel volume was quantified and is represented graphically (g) (*P<0.05 vs. bacteria, #P<0.05 vs. 1 week).
