Table 1 Baseline phenotype in 1-month-old and 3-month-old Lrp6+/+ , Lrp6+/− and Lrp6−/− mice
From: LRP6 in mesenchymal stem cells is required for bone formation during bone growth and bone remodeling
Male | Female | |||||
---|---|---|---|---|---|---|
Lrp6+/+ | Lrp6+/− | Lrp6−/− | Lrp6+/+ | Lrp6+/− | Lrp6−/− | |
Parameter | (n=10) | (n=10) | (n=10) | (n=10) | (n=10) | (n=10) |
1-month-old mice | ||||||
Body mass/g | 24.50±3.04 | 21.85±1.73* | 14.17±2.4* | 21.65±2.33 | 15.9±0.61* | 13.67±3.8* |
Body length/cm | 16.15±1.67 | 15.00±0.71* | 12.86±1.46* | 17.00±1.41 | 13.77±0.40* | 13.50±1.29* |
Tail length/cm | 7.25±1.06 | 6.65±0.50* | 5.86±0.85* | 8.00±0.71 | 6.33±0.23* | 6.11±0.64* |
3-month-old mice | ||||||
Body mass/g | 30.53±2.60 | 27.90±1.43* | 23.7±1.12* | 22.35±1.52 | 19.35±0.97* | 18.30±0.80* |
Body length/cm | 17.00±0.39 | 16.00±0.41* | 15±0.46* | 17.00±0.25 | 15.00±0.21* | 15.00±0.29* |
Tail length/cm | 7.87±0.16 | 6.70±0.24* | 6.50±0.35* | 8.00±0.16 | 6.85±0.43* | 6.75±0.14* |