Table 4 Confocal-based LCS measurements—effects of diabetes

From: The dependences of osteocyte network on bone compartment, age, and disease

 

WT

Akita

Difference/%-(Akita-WT)/WT

Measurement/Unit

Cortical

Cortical

No. of Lacuna

30

30

 

Lacunar volume/μm3

462.4 ± 177.7

403.4 ± 120.0

–12.7% P=0.14

Lacunar surface area/μm2

449.4 ± 129.5

420.3 ± 87.0

–6.5% P=0.31

Lac. major axis/μm

18.3 ± 3.8

18.2 ± 2.8

–0.55% P=0.91

Lacunar density/μm–2

1 073.3 ± 167.8

965.1 ± 132.6

–10.1% P=0.008

Canalicular No.

93.4 ± 23.1

85.53 ± 16.3

–8.5% P=0.13

Canalicular No. density/μm–2

0.210 ± 0.013

0.205 ± 0.022

–2.4% P=0.29

  1. Note: Measurements were made on 20-weeks-old C57BL/6J (WT) and C57BL/6-Ins2Akita/J (Akita) male mice (three animals per group).