Table 5 TEM-based LCS measurements—compartmental comparisons
From: The dependences of osteocyte network on bone compartment, age, and disease
C57BL/6J Mice (15 w) | C57BL/6J Mice (32 w) | C1532Yneo perlecan hypomorph Mice (32 w) | |||||||
|---|---|---|---|---|---|---|---|---|---|
Measurement/Unit | Cortical | Cancellous | Difference | Cortical | Cancellous | Difference | Cortical | Cancellous | Difference |
No. of lacuna | 36 | 32 | 39 | 33 | 39 | 24 | |||
Lac. pericellualr Area/μm2 | 9.28 ± 1.17 | 7.15 ± 1.87 | –22.9% P<0.005 | 7.72 ± 1.88 | 5.27 ± 1.77 | –31.7% P<0.005 | 6.85 ± 1.85 | 2.93 ± 0.87 | –57.2% P<0.005 |
Lac. pericellular thickness/μm | 0.49 ± 0.15 | 0.25 ± 0.04 | –48.9% P<0.005 | 0.47 ± 0.09 | 0.33 ± 0.12 | –29.8% P<0.005 | 0.41 ± 0.09 | 0.20 ± 0.05 | –51.2% P<0.005 |
No. of canaliculi | 721 | 718 | 506 | 334 | 475 | 280 | |||
Canalicular area/μm2 | 0.071 ± 0.029 | 0.072 ± 0.033 | 1.4% P=0.54 | 0.081 ± 0.040 | 0.072 ± 0.032 | –11.1% P<0.005 | 0.066 ± 0.031 | 0.062 ± 0.035 | –6.1% P=0.10 |
Cell process area/μm2 | 0.015 ± 0.008 | 0.021 ± 0.012 | 40% P<0.005 | 0.017 ± 0.013 | 0.021 ± 0.013 | 23.5% P<0.005 | 0.015 ± 0.009 | 0.022 ± 0.016 | 46.7% P<0.005 |
Can. pericellular area/μm2 | 0.056 ± 0.025 | 0.052 ± 0.025 | –7.1% P<0.005 | 0.065 ± 0.034 | 0.052 ± 0.024 | –20% P<0.005 | 0.053 ± 0.026 | 0.041 ± 0.024 | –22.6% P<0.005 |
Can. Pericellular thickness/μm | 0.095 ± 0.028 | 0.084 ± 0.027 | –11.6% P<0.005 | 0.101 ± 0.032 | 0.084 ± 0.028 | –16.8% P<0.005 | 0.089 ± 0.027 | 0.066 ± 0.026 | –25.8% P<0.005 |
