Figure 1
miR-23a/b is gradually downregulated in BMSCs throughout the aging process. (a) qRT-PCR was used to analyze the relative levels of miR-23a/b in BMSCs isolated from C57BL/6 mice of different ages. n=5 per group. (b and c) Comparison of miR-23a/b levels in young and old human BMSCs as determined by qRT-PCR of human male (b) and female samples (c). Male: ny=15, no=17. Female: ny=14, no=15. Data are shown as the mean±s.d. **P<0.01 (ANOVA or Student’s t-test). ANOVA, analysis of variance; BMSCs, bone marrow mesenchymal stem cells; qRT-PCR, quantitative reverse transcription PCR.
