Figure 5 | Bone Research

Figure 5

From: Enhanced but hypofunctional osteoclastogenesis in an autosomal dominant osteopetrosis type II case carrying a c.1856C>T mutation in CLCN7

Figure 5

Expression profiles of OC-related genes. Compared with control OCs, the expression levels of TRAP, RAC1, DC-STAMP, OC-STAMP, and ITGAV in ADO2 cells were similar. However, the expression levels of CTSK, RhoA, and ITGB3 in ADO2 cells were significantly down-regulated, whereas the expression levels of MMP9 and c- fos were significantly increased in ADO2 cells compared with control cells.

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