Figure 6 | Bone Research

Figure 6

From: Enhanced but hypofunctional osteoclastogenesis in an autosomal dominant osteopetrosis type II case carrying a c.1856C>T mutation in CLCN7

Figure 6

Immunofluorescence staining for cytoskeleton-related proteins. (a,b) RAC1. (c,d) Vinculin. (e,f) β-actin. (g,h) Integrin avβ3 and phalloidin-labeled filamentous actin. The control cells showed the even distribution of avβ3 integrin (g). Type II autosomal dominant osteopetrosis (ADO2) osteoclasts (OCs) showed the uneven distribution of the vitronectin receptor (h). The arrows indicate multinuclear cells. avβ3, green; actin, red; nuclear, blue.

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