Figure 2 | Bone Research

Figure 2

From: Abnormal subchondral bone remodeling and its association with articular cartilage degradation in knees of type 2 diabetes patients

Figure 2

Histological changes of cartilage and subchondral bone from non-diabetic and diabetes patients. Cartilage damage was not obviously observed in all the groups on lateral tibial plateau. The analysis showed that there were no statistically significant differences in OARSI score among groups. On medial side, diabetes group showed more obvious disruption of cartilage surface and loss of proteoglycans, and these degenerative changes extended into deeper zone than non-diabetic group. The analysis showed that there were statistically significant differences in OARSI score among groups. Post-hoc tests revealed a significantly higher cartilage OARSI score in diabetes group when compared with non-diabetic group. &P<0.05 among control, non-diabetic and diabetes groups according to one-way ANOVA. #P<0.05 vs non-diabetic group and *P<0.05 vs control group according to Post-hoc tests. AC, articular cartilage; SB, subchondral bone; SP, subchondral plate.

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