Figure 7 | Cell Death & Differentiation

Figure 7

From: SOX2 has a crucial role in the lineage determination and proliferation of mesenchymal stem cells through Dickkopf-1 and c-MYC

Figure 7

Enforced expression of c-MYC can recover the proliferation defects in SOX2-knockdown hUCB–MSCs. (a) The levels of c-MYC and SOX2 were reduced after SOX2 knockdown. LAMIN A and β-ACTIN were used as loading controls. (b) The enforced expression of c-MYC was confirmed by RT-PCR. (c–e) The proliferation of SOX2-knockdown hUCB–MSCs was restored by the addition of c-MYC. The scale bar represents 100 μm. ***P<0.001

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