Table 2 Transcription factors predicted to have their binding sites in the vicinity (±100 bp) of the p53-binding sites

From: Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis

Commmon for induced and repressed

Unique for induced

Unique for Repressed

Factor

N sites per 1 kbp

Enrich

P -value

Factor

N sites per 1 kbp

Enrich

P -value

Factor

N sites per 1 kbp

Enrich

P -value

AHR

0.7117

1.8792

0.001829

BACH2

0.2491

2.587

0.0098112

ARNT

1.7143

2.811

3.59E-05

AP2

5.1246

3.1678

9.43E-40

ETV7

2.9181

1.3733

0.0006481

BCL6

2.0714

1.9207

0.0017116

AP4

1.2278

1.6777

0.0006008

HAND1

4.1815

1.494

7.40E-07

DEAF1

0.2143

33.38

0.0021042

AR

0.3559

2.1322

0.0095111

HNF1A

0.1779

3.9597

0.0049341

HIF1A

1.2143

2.6642

0.0007813

CP2

4.7865

1.6139

7.10E-10

AP1

0.4804

2.5806

0.0004129

    

CREB/ATF

1.9217

1.7404

7.09E-06

MAF

0.1779

6.9295

0.0005729

    

E2F

1.2278

3.4153

1.15E-11

MAZ

0.7117

2.174

0.0002464

    

EBF

0.9431

2.2258

1.73E-05

MYOG

5.8541

1.416

2.89E-07

    

EGR1

0.8363

3.7221

3.98E-09

NFKB

1.121

1.7289

0.0005755

    

ETS1

1.3701

2.1558

6.09E-07

NR3C1

0.1068

16.631

0.0018787

    

HIC1

0.4804

3.7419

7.46E-06

PAX6

8.2206

1.177

0.0020025

    

NR5A2

1.1744

1.5373

0.0037999

SMAD3

4.6085

1.2729

0.0008693

    

PAX3

5.8363

1.2877

0.0001103

SP3

4.2705

1.974

3.22E-15

    

PAX4

1.2811

1.5234

0.0030804

ZBTB33

0.2491

2.985

0.0044078

    

PAX5

6.9751

1.6266

5.52E-14

        

PPARA

6.4057

1.2319

0.000642

        

SP1

1.1566

5.4596

2.06E-16

        

STAT

2.2143

1.8347

0.0022804

        

TEAD-2

1.2989

3.0658

7.00E-11

        

TP53

3.2562

8.0514

4.66E-55

        

V-MYB

0.8541

2.2174

4.48E-05

        

VDR

4.7687

1.6693

6.62E-11

        

WT1

7.0463

2.3304

8.54E-34

        

ZBTB7A

10.854

1.6118

3.70E-20

        

ZF5

7.8114

3.3521

6.24E-64

        

ZFP67

0.7651

11.919

1.58E-16

        

ZIC3

7.8114

1.4215

2.58E-09

        
  1. Expression level after nutlin3a treatment: underlined – induced; bold – repressed; plain – no changes.
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