Figure 6

Impact of loss of PUMA on peripheral blood counts and survival of NHD13 mice. (a) Peripheral blood analysis of Hb, MCV and platelet count in 8-month-old mice (n>6 per genotype). (b) Kaplan–Meier curve analysis for AML-free survival; +/+, wild-type; T/+, transgenic; −/−, knockout; *P<0.05; **P<0.01; ***P<0.001