Figure 1
From: Exploiting death: apoptotic immunity in microbial pathogenesis
Apoptotic externalization of glycolytic enzyme molecules. Many of the protein species involved as enzymes in the intracellular glycolytic pathway of viable cells are enriched among membrane proteins of apoptotic cells and are exposed specifically on the apoptotic cell surface (shown in filled boxes). The externalization of these glycolytic enzyme molecules is a common early event during the process of apoptotic cell death. These externalized molecules fulfill SUPER criteria and are linked to the triggering of IAI (adapted from Ucker et al.12)
