Figure 7 | Cell Death & Differentiation

Figure 7

From: A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR

Figure 7

Individual values of biomarkers measured in brushed nasal cells in all study cohorts throughout the study: CFTR function (a) CFTR band C protein (b) and BECN1 (c). Values are expressed as percentage of non-CF controls (considered as 100% value). Black lines indicate mean values in different cohorts. Red dashed lines indicate 15% (a) and 50% (b and c) of values of non-CF control subjects. Wk, week; Cys, cysteamine; EGCG, epigallocatechin gallate. In treated cohorts Wk 12–20 and Wk 16–24 (italic) indicate the corresponding time points in patients who received the combination treatment for 4 or 8 weeks, respectively. In untreated cohort Wk 12 and Wk 24 indicate the corresponding observational time points throughout the study

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