Figure 3
From: Heterarchy of transcription factors driving basal and luminal cell phenotypes in human urothelium
Chromatin extracts showing bound transcription factors that changed in abundance during differentiation. Factors with motifs detected as enriched in differentiation-specific FAIRE peaks, including GRHL2, GATA3, FOXA1 and PPARĪ³, were upregulated in chromatin extracts from differentiation-induced NHU cells from two independent donors. CTCF and GRHL3 did not change in abundance with differentiation. P63 abundance was reduced after induction of differentiation. Histone H2A is included as a loading control
