Figure 5 | Cell Death & Disease

Figure 5

From: Structural and functional neuroprotection in glaucoma: role of galantamine-mediated activation of muscarinic acetylcholine receptors

Figure 5

RGC functional deficits in glaucoma are improved by galantamine. (a) Visual evoked potentials (VEP) recorded from galantamine-treated normal brains were indistinguishable from those treated with PBS or without treatment. (b) At 3 weeks after OHT surgery, galantamine administration led to marked preservation of the VEP responses (ANOVA, *P<0.001). (c) At 5 weeks after OHT surgery, both PBS-treated and galantamine-treated glaucomatous eyes showed complete obliteration of the VEP response. Daily application of Timolol drops on the cornea was sufficient to restore the VEP response in galantamine-treated eyes but not in PBS-treated eyes (ANOVA, *P<0.001)

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