Figure 3 | Cell Death & Disease

Figure 3

From: Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1

Figure 3

Localization of wild-type and mutated CADM1 in the neurons. Isolated neurons from cadm1-deficient mice embryos (E16) were transfected with wild-type and mutated CADM1 (H246N or Y251S). Their localization at the synapse was examined by immunostaining with anti-SynCAM (Cadm1; red), anti-synaptophysin (green), and Hoechst (blue). Closed arrowheads: CADM1 with no synaptophysin; arrows, neurons with short or no dendrites. Scale bars: 25 μm

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