Figure 4 | Cell Death & Disease

Figure 4

From: Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1

Figure 4

The localization of wild-type and mutated CADM1. (a) C2C5 cells and neurons were transfected with wild-type and mutated CADM1 (Y251S) for 26 h. After fixation, cells were immunostained with anti-SynCAM (Cadm1, green), anti-KDEL (red). (b) Transfected C2C5 cells were immunostained with anti-SynCAM (green), anti-beclin (red), and Hoechst (blue). (c) C2C5 cells were also treated with or without thapsigargin (Thap, 1 μM) for 24 h and were detected by anti-KDEL (green), anti-beclin (red), and Hoechst (blue). Scale bars: 20 μm

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