Figure 6 | Cell Death & Disease

Figure 6

From: Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1

Figure 6

The expression of CHOP in the cells expressing the mutated CADM1 and the mutated neuroligin 3. (a) The mutated CADM1-induced upregulation of CHOP. C2C5 cells were transfected with wild-type, CADM1 (H246N), or (Y251S) cDNA and incubated for 24 h. The upregulation of CHOP was analyzed by immunoblot analysis using anti-CHOP. (b) The percentage of the CHOP-positive cells in the cells expressing wild-type or mutated CADM1s. (c) The percentage of the CHOP-positive cells in the cells expressing wild-type or R451C-mutated neuroligin (NLGN) 3. Scale bars: 5 μm. Bars indicate s.d.

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