Figure 7 | Cell Death & Disease

Figure 7

From: Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells

Figure 7

Androgen delays chronic serum starvation-induced cell death. (a) Time course of cell death of cells maintained in FBS, SF or SF+mib for 24, 48, 72 or 96 h. Cell death was assessed by staining live cells with PI before FACS analysis. (b) Cells were transfected with control or Grp78/BiP siRNA for 24 h, and then treated for a further 72 h with FBS, SF or SF+mib and analysed as in (a). n=3, error bars indicate mean S.E. *P<0.05 and **P<0.01 as indicated; #P<0.05 versus corresponding control

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