Figure 2 | Cell Death & Disease

Figure 2

From: GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy

Figure 2

GX15-070 has lethality effect in both Dex-sensitive and -resistant ALL cells. (a) ALL cell lines including CEM, Molt-4, Jurkat, Reh, or HSB-2 were treated with 100 nM GX15-070 (GX) for indicated times and growth rate was determined by WST-1 colorimetric assay. Error bars represent the standard error of three independent experiments. (b) Cells were treated with 100 nM Dex and/or 100 nM GX15-070 for 48 h. The percentage of cell death was determined by Annexin V-PI staining followed by FACS analysis. Values represent the mean±S.D. of three independent experiments

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