Figure 6
From: Enhanced neuronal Met signalling levels in ALS mice delay disease onset
Tissue-distribution of activated chimeric Met in adult brains and spinal cords. (a and b) Sagittal sections of adult brains showing phospho-Met staining in Nes-R26Met, but not in R26LacZ−stop−Met mice. (c–h) Enlarged view of phospho-Met distribution in the lateral ventricle (c), pons (d), cervical spinal cord (e), corresponding to regions indicated by squares in panel (a). Distribution of phospho-Met in the hippocampus (f), olfactory bulb (g), and lumbar spinal cord (h). Arrowheads in (e and h) point to phospho-Met-positive cells with large nuclei resembling MNs. cb, cerebellum; cc, cerebral cortex; lv, lateral ventricle; ob, olfactory bulb; p, pons; sc, spinal cord
