Figure 5

Activation of CaspACE–VAD–FMK binding cysteine proteases in P. falciparum parasite. (a) Graph showing percentage of CaspACE-tagged parasites in the cultures at different time points (4, 6, 8, and 16 h) after treatment with peptides Ant-FI, Ant-Scrambled (Ant-Scr) or solvent alone. (b) Flow cytometry histogram showing population of CaspACE-tagged parasites in cultures 4 h after Ant-FI treatment as compared with controls