Figure 6

DNA fragmentation in P. falciparum parasites as assessed by TUNEL staining. (a) Graph showing percentage of TUNEL-positive parasites in the cultures at different time points (4,6,8 and 16 h) after treatment with peptides Ant-FI (50 and 90 μM), Ant-scrambled (Ant-Scr, 90 μM) or solvent alone. (b) Fluorescent microscopic images of TUNEL-positive parasites (TdT red staining) in treated cultures as compared with controls. The parasite nuclei were stained with DAPI (blue) and parasites were visualized by fluorescence microscope