Figure 5 | Cell Death & Disease

Figure 5

From: Functional and biochemical characterization of the baculovirus caspase inhibitor MaviP35

Figure 5

MaviP35 inhibits recombinant caspases in vitro. Cleavage of fluorogenic substrates by purified recombinant caspases (at the indicated concentrations) is plotted as the change in RFU per minute, in the presence of 1 μM of FLAG-tagged MaviP35, AcP35 or truncated CED-9 (a cytosolic protein devoid of caspase inhibitory activity). The dotted line indicates 10% activity, relative to the substrate cleavage rate in the presence of the control protein

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