Figure 6
From: Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis
Caspase-independent hyperoxia-induced apoptosis is regulated by TRP601 treatment. Densitometric quantification of AIF expression by western blotting demonstrates a significant upregulation of AIF expression in thalamic samples of hyperoxia-treated rat pups after 12 and 24 h, which is prevented by TRP601 treatment. The densitometric data represent the ratio of the density of the AIF band to the corresponding β-actin band. Data are normalized to levels of rat pups exposed to normoxia (control 100%; bars represent mean±S.E.M.; n=6/group, ***P<0.001, ###P<0.001, one-way ANOVA compared with respective controls). Blots are representative of a series of three blots
