Figure 1 | Cell Death & Disease

Figure 1

From: Axonal remodeling for motor recovery after traumatic brain injury requires downregulation of γ-aminobutyric acid signaling

Figure 1

Downregulation of GABAAR subunit expressions in the contralesional cortex after traumatic brain injury. (a–c) Quantification of the mRNA expression of GABAAR subunits (α (a), β (b), and γ and δ (c) subunits) in the contralesional cortex at 7 days after brain injury (by real-time PCR). The fold change of the injured group (black bars) relative to the sham group (gray bars) is shown as the mean±S.D. (n=3, each group). (d) Western blots of the GABAAR-α1 subunit and NCAM (internal control) in the contralesional cortex at 1, 2, and 4 weeks after the injury. (e) Quantification of GABAAR-α1 protein expression in d. The expression significantly decreased at 1 and 2 weeks after the injury. (n=6, each group). *P<0.05 (Mann–Whitney U-test)

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