Figure 6 | Cell Death & Disease

Figure 6

From: Isthmin exerts pro-survival and death-promoting effect on endothelial cells through alphavbeta5 integrin depending on its physical state

Figure 6

Immobilized ISM activates FAK and promotes EC haptotactic migration. (a) Immobilized ISM activates FAK Y397 phosphorylation in similar fashion as immobilized VN. S, cells in suspension. (b) ISM dose-dependently promotes EC haptotactic migration with similar potency as FN. (c) ISM promotes EC haptotactic migration through αvβ5 integrin

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