Figure 3
From: Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage
APAP induces Bim protein expression. Human hepatocytes (a), HepG2 (b) or IHH (c) cells were treated with APAP, TRAIL or both for 6 h, and Bim protein expression was analyzed by western blot. (d) Liver samples of PBS- or APAP-treated wild-type mice were analyzed for the expression of Bim by western blot. JNK or tubulin was used to normalize protein loadings
