Figure 1
From: Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy
Microscopic appearance of parental HepG2 cells after exposure to a single dose of 10-Gy X-rays. (a) Mitotic figures but a few were observed in HepG2 cells without irradiation. (b) No remarkable changes but the increase in cell size were observed 1 day after exposure. (c) The increase in cell size was obvious 2 days after exposure. (d) Mitotic figures were apparent 3 days after exposure (black arrows). (e) At day 5 after exposure, a frequent number of dying cells were seen (black arrow heads). Multinucleated cells showing mitotic catastrophe were also increased (white arrows). (f) At day 7 after exposure. (g) Dead cells with apoptotic bodies (arrow heads; 5 days after exposure to X-rays). (h) Dead cell without apoptotic bodies (arrow head; 5 days after exposure to X-rays)
