Figure 7

(a–d) Combined effect of FR of 2 Gy of X-rays (FR) and RPM on cell growth. (a) RPM (10 ng/ml) did not affect cell growth of HepG2. (b) RPM significantly suppressed cell growth of HepG2-8960-R without radiation. (c) Until cumulative dose of 10 Gy, RPM did not affect cell growth of HepG2. (d) Cell growth of HepG2-8960-R was significantly suppressed by the administration of RPM with cumulative 10 Gy of X-rays. (e–h) Combined effect of fractionated 2 Gy of X-rays and administration of 3-MA on cell growth. (e) Cell growth of HepG2 was suppressed by the administration of 3-MA, but no significance was detected at any point examined. (f) Administration of 3-MA had no effect on cell growth of HepG2-8960-R cells. (g) Cell growth of HepG2 with fractionated 2 Gy of X-rays was not significantly different between with and without 3-MA. (h) Cell growth of HepG2-8960-R with fractionated 2 Gy of X-rays was not different between with and without 3-MA. Mean±S.D. of three independent experiments were calculated. ^*P<0.01