Figure 7
From: Apical membrane rupture and backward bile flooding in acetaminophen-induced hepatocyte necrosis
Transmission electron microscopy showing a dead hepatocyte able to depict consequences post-apical membrane rupture. (A) A shrunk hepatocyte indicated by arrows was devoid of organelles. Most of its content has ground-glass appearance. (B) Magnified photo of boxed area b in A shows bile lakes with ragged margins. (C) Magnified photo of boxed area c in A shows remaining organelles in the dead hepatocyte were clustered together. b.c.=bile canaliculus; b.l.=bile lakes. Scale bars indicate 2 μm in A and 200 nm in B and C
