Figure 7
From: CYLD regulates keratinocyte differentiation and skin cancer progression in humans
CYLDWT expression decreases tumor angiogenesis, while loss of CYLD function enhances the vascularization of skin tumors. (a–c) CD31 staining of blood vessels. Note the smaller size of the vessels in the A-CYLDWT tumors compared with that of A-CYLDC/S SCCs. (d–f) SMA staining. Representative tumors are shown in each panel. Similar data were obtained in five tumors of each genotype. Arrows in (e) indicate the blood vessels. Arrowheads in (f) mark the extremes of the blood vessels. Six tumors of each type were analyzed
