Figure 2 | Cell Death & Disease

Figure 2

From: Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

Figure 2

The inhibitory effect of metformin on growth of human lymphoma cell lines. (a) IC50 results obtained from MTT assay in a series of B- and T-lymphoma cell lines after metformin treatment. (b and c) Response curves (b) and AMPK/ACC expression detected by western blot (c) in malignant B and T cells treated with metformin. (d) Metformin inhibited growth of primary lymphoma cells. (e) The proliferation of CD34+ cells enriched from cord blood samples was not altered by metformin up to 120 mM

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