Figure 6

Remnant living cells expressing HSV1-tk are sensitive to GCV. (a) Western blot analysis compared the expression of the HSV1-tk reporter gene in ex vivo 4T1-PB-2R/PBase cells and the original transduced 4T1-PB-2R/PBase cells. (b) MTT assay compared the viability between HSV1-tk-expressing CSC-like cells and parental 4T1 cells after GCV treatment. Each datum represents the mean of five independent experiments±S.D. *P<0.05