Figure 5 | Cell Death & Disease

Figure 5

From: A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation

Figure 5

HMQ18–22 inhibited tumor growth in nude mice bearing human colon cancer xenografts. (a) The representative xenografts of lovo human colon cancer in mice. (b) HMQ18–22 decreased the phosphorylation of VEGFR2(Tyr1214), VEGFR1(Tyr1333), Akt(Tyr326), PKCα (Tyr657) and PLCγ-1(Tyr771) in the tumor tissues by western blot analysis. (c) Quantitation data of (b). Data were expressed as mean values±S.D. (n=3). **P<0.01 versus the untreated control

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