Table 1 Phosphorylation sites identified on eEF1A1 and eEF1A2 expressed in Escherichia coli

From: Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells

Kinases

Substrates

Phosphopeptide sequence

Modified amino-acid residue

B-Raf

eEF1A1-His

K.pSTTTGHLIYK.C

S21

B-Raf

eEF1A1-His

K.YYVpTIIDAPGHRDFIK.N

T88

B-Raf

eEF1A2-His

K.pSTTTGHLIYK.C

S21

C-Raf DD

eEF1A1-His

–

–

C-Raf DD

eEF1A2-His

K.pSTTTGHLIYK.C

S21

C-Raf DD

eEF1A1-His+eEF1A2-His

K.pSTTTGHLIYK.Ca

S21

  1. aPhosphopeptide not ascribable specifically to any of two eEF1A isoforms
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