Figure 1 | Cell Death & Disease

Figure 1

From: uPAR and cathepsin B shRNA impedes TGF-β1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway

Figure 1

Meningioma tumors express TGF-β1. (a) Immunohistochemical analysis for TGF-β1 was performed on the tissue microarrays of clinical meningioma samples. Representative images of whole array and different meningioma types ( × 400) are shown. (b) Immunoreactivity for TGF-β1 was plotted as percent positivity under different categories. Scoring was made for the reactivity as negative, less reactive, and highly reactive. (Others; atypical (n=2), psammomatous (n=2), microcapsule (n=2), chordoid (n=1), sparse (n=1), and papillary (n=1)). Each picture or value is a representative or mean of three independent arrays. (c) IOMM-Lee and CH157-MN cell lysates were subjected to immunoblotting for TGF-β1. GAPDH served as loading control. Each blot is representative of three independent experiments

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