Figure 6 | Cell Death & Disease

Figure 6

From: Cordyceps militaris and mycelial fermentation induced apoptosis and autophagy of human glioblastoma cells

Figure 6

Involvement of kinase activity in the CM-induced cytotoxicity in human glioblastoma cells. GBM8401 (a) and U-87MG (b) cells cultivated in a 96-well plate were pretreated with either 0.1% dimethylsulfoxide (DMSO) as solvent control or with 10 μM of selective kinase inhibitors, including SB203580 (SB), SP600125 (SP), PD98059 (PD), and wortmannin (WM), at 2 h before treatment with or without 2 mg/ml of mycelial fermentation (MF) of CM. After 24 h of treatment, the CM-driven cytotoxicity was evaluated by MTT assay. Data are presented as mean±S.D. from three independent experiments. *P<0.05, as compared between groups; #P<0.05, as compared with corresponding MF(−) groups; &P<0.05, as compared with negative control (NC) groups using Student’s t-test

Back to article page