Figure 1

MiR-203 expression in mouse skin after wound infliction. Histological analysis of the wounded mouse epidermis at days 3 and 5 after wounding. From the top: H&E, in situ hybridization performed using a specific miR-203 probe, IHC analysis of K6. Black bars: 100 μm. Each panel is a composition of six images taken with an × 10 objective to provide high resolution over a wide area, whereas the insets are a magnification ( × 20) of the identified squared boxes: left box, upper inset; right box, lower inset. Black bar in the insets: 20 μm. (epi: epidermis; der: dermis; GT: granulation tissue). In H&E staining panels, red arrows indicate the wound edge. Negative controls for the in situ hybridization are shown in Supplementary Figure S1